Lipemia (T173) [Back]
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| RISK ASSESSMENT VALUE: |
Lipemia in a serum sample is most commonly the result of a non-fasting status. There is a rare inherited metabolic disorder that results in the over production of fats in some people. An excessive amount of triglyceride in a serum sample is responsible for lipemia. Other laboratory results are known to be affected by lipemia. In non-fasting samples it is possible to separate out, via ultracentrifugation, the excess lipids and obtain more accurate values that approximate those found in a fasting sample. 15 minute ultracentrifugation will not separate serum lipids present in genetic hyperlipidemia.
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| NORMAL RESULTS: |
The following tests are generally not affected:
Glucose
Creatinine
Calcium
GGTP
Total Protein
Cholesterol
HDL (may show slight increase)
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| ABNORMAL RESULTS: |
The following tests are usually flagged with an instrument error and require re-analysis either after ultracentrifugation or dilution:
BUN
SGOT
SGPT
LDH
Bicarbonate
The following tests are usually increased as a result of lipemia:
Uric acid
Bilirubin
Albumin
Fructosamine
Triglyceride
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| ADDITIONAL TESTS: |
Not applicable.
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| SAMPLE NEEDED: |
Separated serum from a red-stopper tube.
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| SAMPLE STABILITY: |
Ten (10)days at room temperature, 2 weeks when refrigerated and indefinite when frozen at <20?c.
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| METHOD & INSTRUMENT: |
Methodology - Reagent Blank; Instrumentation - Hitachi Modular.
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| INTERFERING FACTORS: |
If triglycerides are >400, the calculated tests (i.e. VLDL, LDL) are not reported.
If triglycerides are >800, ultracentrifugation is performed. Results are reported on the clarified sample.
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| PURPOSE: |
" To provide additional information to the underwriter in regards to specimen condition and the accuracy of laboratory results.
" Method to reduce the affect of postprandial lipids on sample results.
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| PROFILE INCLUDES: |
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| RISK RANGE & UNITS: |
0-45 NORMAL
46-130 MODERATE
>131 HEAVY
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